Villitis of unknown etiology

Villitis of unknown etiology
Classification and external resources

Micrograph of villitis of unknown etiology. H&E stain.

Villitis of unknown etiology, abbreviated VUE, is an inflammatory process that involves the chorionic villi (villitis) those cause (etiology) is not known. VUE is associated with recurrent miscarriage and intrauterine growth restriction,[1] and recurs in subsequent pregnancies.[2]

Contents

Histopathology

Histomorphologically, VUE is characterized by a lymphocytic infiltrate of the chorionic villi without a demonstrable cause. Plasma cells should be absent; the presence of plasma cells suggests an infective etiology, e.g. CMV infection.

See also

Additional images

References

  1. ^ Redline, RW. (Oct 2007). "Villitis of unknown etiology: noninfectious chronic villitis in the placenta.". Hum Pathol 38 (10): 1439–46. doi:10.1016/j.humpath.2007.05.025. PMID 17889674. 
  2. ^ Feeley L, Mooney EE (2010). "Villitis of unknown aetiology: correlation of recurrence with clinical outcome". J Obstet Gynaecol 30 (5): 476–9. doi:10.3109/01443611003802339. PMID 20604650.